Multiple Myeloma with Intracytoplasmic Azurophilic Granules

(2019) Multiple Myeloma with Intracytoplasmic Azurophilic Granules. Int J Hematol Oncol Stem Cell Res. pp. 58-60. ISSN 2008-3009 (Print) 2008-2207 (Linking)

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Abstract

Bone marrow examination plays an important role in the diagnosis of multiple myeloma. In some cases with multiple myeloma, marrow plasma cells with cytoplasmic inclusions are seen. In this study, a 46-year- old man was evaluated for multiple myeloma. In bone marrow aspiration, large intracytoplasmic azurophilic granules, resembling intracellular microorganisms were seen. IHC study demonstrated that these cells are CD138 positive. This is a rare histologic finding that usually results from the deposition of excess immunoglobulin.

Item Type: Article
Keywords: Azurophilic granules Multiple myeloma Plasma cell
Subjects: QZ Pathology > QZ 140-180 Pathologic Processes
QZ Pathology > QZ 200-380 Neoplasms
Divisions: Cancer Prevention Research Center
Faculty of Pharmacy and Pharmaceutical Sciences > Department of Clinical Pharmacy and Pharmacy Practice
Other
Page Range: pp. 58-60
Journal or Publication Title: Int J Hematol Oncol Stem Cell Res
Journal Index: Pubmed
Volume: 13
Number: 2
ISSN: 2008-3009 (Print) 2008-2207 (Linking)
Depositing User: Zahra Otroj
URI: http://eprints.mui.ac.ir/id/eprint/11755

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