Cutaneous necrosis after the injection of sodium stibogluconate for the treatment of cutaneous leishmaniasis: A rare case report

Abstract

A 32-year-old man was diagnosed with cutaneous leishmaniasis, and intradermal Sodium Stibogluconate was injected for him. After two days, the injection site became erythematous, and a progressive necrotizing lesion appeared; hence, the patient diagnosed with soft tissue infection. Antibiotic therapy and debridement initiated for him. Cutaneous adverse effect of Sodium Stibogluconate is not common, and among them, coetaneous necrosis is rare. Sodium Stibogluconate is a mixture of complex compound, and it is not a simple medicine. A probable mechanism of necrosis formation in this case is hypersensitivity reactions. Hence, it is suggested to avoid intradermal injection of this medicine, especially those brands which do not claim intradermal injection allowance. © 2019, Isfahan University of Medical Sciences(IUMS). All rights reserved.