Urinary concentrations of parabens amongst Iranian adults and their associations with socio-demographic factors

(2020) Urinary concentrations of parabens amongst Iranian adults and their associations with socio-demographic factors. Journal of Environmental Health Science and Engineering. pp. 1227-1238. ISSN 2052-336X

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Abstract

Background Parabens are widely used to prevent organism growth and increase the shelf life of foods, medicines and personal care products (PCPs). Recent studies indicate their potentially harmful effects on human health. There is no information on the extent of exposure to parabens among Iranians. Methods We measured the concentration of urinary methylparaben (MP), ethylparaben (EP), propylparaben (PP) and butylparaben (BP) among Iranian adults and calculated their estimated daily intake (EDI). Also, association between the level of urinary parabens with socio-demographic and lifestyle variables were investigated. Results Detection frequencies of MP, EP, PP, and BP were 98.9, 91, 94.3, and 88.2, and their median urinary concentrations were 69.06, 9.10, 12.4, and 9.87 mu g/l, respectively. Urinary parabens were higher in females, and the difference in the concentration of MP and PP was significant. A significantly positive correlation between MP and PP (r = 0.638) and a moderate to a weak correlation between other parabens were observed. There was a significantly negative weak correlation between age and MP, BP and PP. There was also a significant association between different age groups and MP, BP and PP as well as different BMI values and MP. The highest EDI value belonged to MP in the female group. Despite being lower than the acceptable daily intake (ADI), its value was higher than that reported in other countries (except the US). Conclusions Our findings indicated that Iranians are widely exposed to the parabens and the range of exposure was associated with socio-demographic factors. These results could serve as a basis for assessing the risk of exposure to parabens amongst Iranians.

Item Type: Article
Keywords: Parabens Urine Biomonitoring Adults Estimated daily intake PERSONAL CARE PRODUCTS P-HYDROXYBENZOIC ACID BISPHENOL-A DEMOGRAPHIC-FACTORS PHTHALATE METABOLITES ESTERS PARABENS HUMAN EXPOSURE UNITED-STATES TRICLOSAN PHENOLS
Subjects: WA Public Health > WA 670-847 Environmental Pollution. Sanitation
WA Public Health > WA 900-950 Statistics. Surveys
Divisions: Behavioral Sciences Research Center
Faculty of Health > Department of Epidemiology and Biostatistics
Faculty of Health > Student Research Committee
Research Institute for Primordial Prevention of Non-communicable Disease > Environment Research Center
Page Range: pp. 1227-1238
Journal or Publication Title: Journal of Environmental Health Science and Engineering
Journal Index: ISI
Volume: 18
Number: 2
Identification Number: https://doi.org/10.1007/s40201-020-00540-6
ISSN: 2052-336X
Depositing User: Zahra Otroj
URI: http://eprints.mui.ac.ir/id/eprint/12540

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