Incidence of Colorectal Cancer and Adenomatous Polyps After a Two-Step Screening in Isfahan Province, Iran in 2018

Abstract

Purpose The aim of this study was to estimate the incidence of colorectal cancers in Iran. The results of this study are based on a screening program that is being implemented in Isfahan province. Material and Methods In this study, about 137,000 people were screened for colorectal cancer and adenomatous polyps in 2 steps during the year 2018. Results Based on the findings of this study, the incidence of adenomatous polyps was reported to be 389 (95 CI, 365-422) per 100,000 population. The incidence of adenomatous polyps was reported to be 483 (95 CI, 446-520) and 316 (95 CI, 286-346) in men and women, respectively (p < 0.001). Also, the incidence of colorectal cancer was reported to be 33 (95 CI, 23-42) per 100,000 population. The incidence of colorectal cancer in men and women was reported to be 41 (95 CI, 30-51) and 26 (95 CI, 17-34), respectively, indicating a statistically non-significant difference (p = 0.29). Conclusion Based on the result of this study, despite a low participation rate of the target population in the screening program, the incidence of adenomatous polyps and colorectal cancer is relatively high in the average-risk population.