(2021) Acute lymphoblastic leukemia switch lineage upon relapse to acute bilineage leukemia: A case report. Iranian Journal of Blood and Cancer. pp. 22-25. ISSN 20084595 (ISSN)
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Abstract
Although acute leukemia commonly relapses in adults, the conversion of leukemic cell lineage (lymphoid or myeloid) upon relapse has rarely taken place. “Lineage switch” is a term widely used to define the leukemic lineage transformation as assessed by morphology, cytochemistry, and immunophenotyping from diagnosis to relapse. In most lineage switch cases, B-cell lymphoblastic leukemia/ lymphoma relapses as acute myeloid leukemia or vice versa. Here, we report an exceedingly rare case of T-cell acute lymphoblastic leukemia relapsing as mixed-phenotype acute leukemia. © 2021, Iranian Pediatric Hematology and Oncology Society. All rights reserved.
| Item Type: | Article |
|---|---|
| Keywords: | Acute bilineage leukemia Acute lymphoblastic leukemia (ALL) Lineage switch Mixed-phenotype acute leukemias (MPALs) |
| Page Range: | pp. 22-25 |
| Journal or Publication Title: | Iranian Journal of Blood and Cancer |
| Journal Index: | Scopus |
| Volume: | 13 |
| Number: | 1 |
| ISSN: | 20084595 (ISSN) |
| Depositing User: | Zahra Otroj |
| URI: | http://eprints.mui.ac.ir/id/eprint/14746 |
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