Correlation between stable hyperglycemia and mortality in children admitted to the pediatric intensive care unit of Imam Hossein Hospital

Abstract

Background: Stress-induced hyperglycemia is an important issue among pediatrics admitted in the pediatric intensive care unit (PICU). Former studies have declared that hyperglycemia has a high prevalence rate and could increase the risks of mortality among pediatrics. Here, we aimed to investigate the prevalence rate of hyperglycemia and its effects on mortality among pediatrics in the PICU of the hospital. Materials and Methods: This cross-sectional study was performed in 2018-2019 on 88 patients admitted in PICU. Data regarding blood sugar (BS) and other clinical and laboratory parameters were collected. Hyperglycemia was accounted for as BS of >126 mg/dl. Hyperglycemia was divided into: mild (126 <BS <150), moderate (150 <BS <200) and severe (BS >200). The pediatric risk of mortality (PRISM) score was also calculated for each patient during the first 24 h. Results: Thirty patients (34.1) had persistent hyperglycemia and 58 patients (65.9) had normal glycemic indexes. Eleven patients (12.5) had mild, 9 patients (10.2) had moderate, and 10 patients (11.4) had severe hyperglycemia. The prevalence of mortality was 5.7 among hyperglycemic patients and 6.8 among normal glycemic pediatrics. There were no statistically significant differences regarding mortality rate (P = 0.499). The mean PRISM score for normal glycemic patients was 7.03 +/- 5.18 and for patients with hyperglycemia was 7.36 +/- 6.37. Conclusion: Hyperglycemia has no significant effects on mortality and PRISM score of pediatrics in PICU, despite of the previous studies. The frequency of hyperglycemia was also 5.7 among the patients admitted in PICU.