Role of dietary antioxidants and vitamins intake in semen quality parameters: A cross-sectional study

Abstract

Background & aims: : Infertility had an increasing trend among couples in Iran. Several factors such as lifestyle, physical activity, unhealthy dietary habits and stress are associated with production of ROS in seminal fluid. The aim of this study was to identify the role of dietary antioxidants and vitamins intake on semen quality parameters, among Iranian infertile men. Methods: This cross-sectional study was performed on 400 newly diagnosed infertile men in Yazd Reproductive Sciences Institute from July 2019 to December 2019. The presence of infertility was confirmed by an expert andrologist, based on WHO criteria. Dietary antioxidants and vitamins intake were assessed using a 168 items semi-quantitative food frequency questionnaire (FFQ). Results: We found an association between total motility and beta-Cryptoxanthin dietary intake in the full adjusted model (P = 0.03). Although a significant relationship was observed between b-Cryptoxanthin and normal morphology in the crude model, the association became non-significant after controlling for confounders. No further significant association was detected between antioxidant and nutrients, and fertility-related parameters. Conclusions: Present study suggests that dietary intake of b-Cryptoxanthin might be associated with an improvement in sperm motility. However, more research is needed to confirm these relations and provide the evidence needed to exert these findings into clinical practice. (C) 2022 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.