Medical Evaluation of Test Results Related to Covid 19 in Iranian Hospitals Using QUADAS-2 to Evaluate the Quality of Studies and Meta-Analysis Using Stata / MP v.16 Software

Abstract

The aim of current study was to evaluate the outcome of some laboratory tests and accuracy of diagnostic tests for patients with COVID-19. The QUADAS-2 tool was utilized to quality assessment of diagnostic accuracy studies. For data extraction, two reviewers blind and independently extracted data from abstract and full text of studies that included. 95 confidence interval for effect size with fixed effect model and Inver-variance method were calculated. Meta-analysis was performed using Stata/MP v.16 software. 469 studies were reviewed, of which the full text of 52 studies was reviewed and finally twenty-two studies were selected for meta-analysis. Mean differences of Alanine transaminase was 3.40 U/L (MD, 95 CI -2.45, 9.25), correlation between Alanine transaminase and severe COVID-19 was not significantly. Stool, feces, rectal swabs 25 (ES, 95 CI 0.32, 0.82), Urine 1 (ES, 95 CI 0.05, 0.58), overall sensitivity of PCR for detection of COVID-19 was 44 (ES, 95 CI 0.19, 0.68), less sensitive observerd when PCR detection of COVID-19. Evidence revealed that at the time of admission of patients with COVID-19, a specific laboratory model can be used to perform relevant tests and make decisions about patients. PCR using sputum samples was highly sensitive for detecting COVID-19 and after that computed tomography of the chest was identified with high sensitivity. © 2022 by SPC (Sami Publishing Company).