Evaluation of a treatment planning system for applying the effect of titanium clips on isodosedistribution in radiation therapy of colorectal cancer

(2017) Evaluation of a treatment planning system for applying the effect of titanium clips on isodosedistribution in radiation therapy of colorectal cancer. Journal of Isfahan Medical School. pp. 686-691. ISSN 10277595 (ISSN)

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Abstract

Background: In laparoscopy of colorectal tumors, titanium clips are used to close the surgery site. For post-operation treatment with radiation, the clips might change the dose distribution. In this study, the effect of titanium clips in isodose distribution of 6- and 18-MV photons was evaluated. Methods: Laparoscopy clips were placed on a phantom with material close to soft tissue. Computed tomography (CT) scan images of this phantom were imported in planning software and the percentage depth dose (PDD) and profiles of the dose were obtained for 6- and 18-MV photons. Findings: Calculated PDD showed weakening and backscattering of the dose of radiation in the path after the clips. Dose changes for the regions after the clips had a maximum of 1.7 and 1.1 for 6- and 8-MV photons, respectively. The amount of backscattering was up to 0.4 and 0.7 for 6- and 18-MV photons, respectively. Conclusion: Presence of the titanium clips in the path of radiation changes the depth dose and profiles. The changes for of a single clip are minor. However, for few clips beside each other, the effect of radiation attenuation is not negligible. © 2017, Isfahan University of Medical Sciences(IUMS). All rights reserved.

Item Type: Article
Keywords: Colorectal tumors Computer-assisted Radiation dosages Radiotherapy planning Article cancer radiotherapy colorectal cancer computer assisted tomography medical device percentage depth dose pharmacokinetic parameters radiation dose radiation scattering radiotherapy planning system titanium clip
Divisions: Faculty of Medicine > Department of Basic Science > Department of Medical Physics
Faculty of Medicine > Departments of Clinical Sciences > Department of Surgery
Page Range: pp. 686-691
Journal or Publication Title: Journal of Isfahan Medical School
Journal Index: Scopus
Volume: 35
Number: 434
ISSN: 10277595 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.mui.ac.ir/id/eprint/1878

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