Demographic and some underlying factors in patients with sepsis in Alzahra Hospital, Isfahan, Iran

Abstract

Background: Sepsis is one the ten main causes of death in hospitalized patients. Due to high prevalence of sepsis and other related syndromes, adverse effects of this syndrome and high rate of death due to sepsis in patients admitted to Alzahra Hospital, Isfahan, Iran, we decided to evaluate associated factors, demographic data, and underlying diseases which may develop sepsis in patients referred to this hospital. Methods: This was a cross-sectional study on 229 patients with criteria of sepsis referred to Alzahra hospital during 2011-15. Demographic characteristics were recorded. Patients were evaluated base on the immunity status. Patients’ blood, urine, and wound specimens underwent culture. P < 0.05 was considered as significant. Findings: The mean age of patients was 69.17 ± 17.84 years. 52 of patients were male and 48 were female. The mean age and duration of hospitalization were 71.82 ± 17.27 years and 9.93 ± 9.55 days among dead and 85.43 ± 18.06 years and 13.40 ± 9.70 days among improved patients (P = 0.007 and P = 0.008, respectively). Immunodeficiency did not play significant role in prognosis of sepsis (P = 0.795) while the etiology of pneumonia (P = 0.030) and being bedridden (P < 0.001) had significant role in prognosis of sepsis. Conclusion: According to this study, age, being bedridden, underlying disease, and also immunodeficiency can be considered as independent factors for sepsis prognosis. © 2017, Isfahan University of Medical Sciences(IUMS). All rights reserved.