The Correlation between Coronary Artery Calcium Score with Diagnosis of Angina Pectoris in Patients with and without Metabolic Syndrome, Candidates for Coronary Angiography

Abstract

Background: The coronary artery calcium score is a reliable measure of coronary atherosclerosis. This study evaluated the relationship between coronary artery calcium score, cardiovascular events, and metabolic syndrome. Methods: This cross-sectional study was performed in Al-Zahra Hospital in 2019 and included patients who referred to the emergency department of Al-Zahra Hospital with a complaint of typical and atypical chest pain and admitted to the emergency ward of the hospital. Those with a pre-test probability between 5-15 percent underwent coronary CT angiography and their coronary calcium score was calculated and recorded. The data were analyzed using Mantel-Haenszel Chi-square statistical tests of two domains and correlation test (Bivariate Correlations). Findings: The correlation between metabolic syndrome and coronary artery calcium score was meaningful. The odds ratio of men with metabolic syndrome with a coronary artery calcium score was about 4 times higher than women. After adjusted for gender by Mantel-Haenszel method, the chance of developing metabolic syndrome and coronary artery calcium score of 1 or above was 9.96. With bivariate correlations test, the correlation between coronary artery calcium score and metabolic syndrome was statistically significant. Conclusion: Coronary artery calcium score is more common in patients with metabolic syndrome (MetS) and these are two valuable predictors for coronary artery disease. © 2022 Isfahan University of Medical Sciences(IUMS). All rights reserved.