Prenatal and clinical characteristics of pregnant women infected with COVID-19 in Yazd, Iran: A multicenter cross-sectional study

Abstract

BACKGROUND: Coronavirus infection has caused widespread concern among mothers and physicians about the health of pregnant women and infants. OBJECTIVE: The aim of this study was to evaluate the clinical and prenatal findings of pregnant women with coronavirus disease-2019 (COVID-19) virus. MATERIALS AND METHODS: The present study was a descriptive study that was conducted in 6 mother and child care centers. In this study, 81 pregnant women with COVID-19 admitted to centers in the period from March 2020-September 2020 were studied. Clinical and prenatal findings of the pregnant mothers were recorded using a data collection form with details of demographic characteristics and these were analyzed. RESULTS: The gestational age of the affected women was between 4 and 40 wk. 48 deliveries were performed and 25 of deliveries were preterm. Coronavirus infection was the cause of termination of pregnancy in 4 cases. The most common symptoms of women when visiting the medical centers were: dry cough (58.0), muscle pain and myalgia (56.8) and fever (51.9). The most common laboratory findings in the women were: increased C-reactive protein (67.90), lymphopenia (18.51), decreased white blood cells (27.16), and increased liver enzymes (18.51). Regarding the status of the newborns, out of the 33 neonates examined, 3 neonates were diagnosed with COVID-19. CONCLUSION: The most common symptoms of pregnant women with COVID-19 are similar to those of other adults. In relation to neonatal infection, given that a number of the neonates tested positive, there appears to be evidence of vertical transmission, which requires further investigation.