(2025) Fatal Postoperative Mucormycosis Following Emergency Abdominal Surgery in an Immunocompetent Patient: A Case Report and Literature Review. Infectious Microbes and Diseases. ISSN 20967241 (ISSN)
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Abstract
Mucormycosis is a rare and severe fungal infection that typically affects immunocompromised individuals, although it has increasingly been reported in immunocompetent patients. Postoperative mucormycosis, particularly following emergency abdominal surgery, is an exceedingly rare complication. We present the case of a man in his late 30s who developed fatal postoperative mucormycosis after an emergency laparotomy for trauma. Despite prompt initial antifungal treatment with amphotericin B, the infection rapidly progressed, leading to sepsis and death. This case of postoperative mucormycosis in an immunocompetent patient in Iran is unusual and emphasizes the need for a high index of suspicion for rare infections such as mucormycosis, even in patients without traditional risk factors. Early antifungal therapy, close monitoring, and prompt multidisciplinary management are critical for improving outcomes. © 2025
| Item Type: | Article |
|---|---|
| Keywords: | fungal infection necrosis postoperative mucormycosis Rhizopus sp amphotericin B lipid complex antibiotic agent bicarbonate C reactive protein hypertensive factor abdominal pain abdominal quadrant abdominal radiography abdominal surgery abdominal swelling abdominal tenderness adult anastomosis Article artificial ventilation bicarbonate blood level blood pressure body temperature case report clinical article computer assisted tomography death disease exacerbation diverticulosis emergency surgery emergency ward fatality fever fungus culture general condition deterioration heart rate histopathology hospital admission hospitalization human human tissue hypotension immunocompetence intraoperative period Iran jejunum disease laboratory test laparotomy leukocyte count leukocytosis male metabolic acidosis mucormycosis multiple organ failure nausea and vomiting necrotic tissue pain severity patient transport peritonitis postoperative complication postoperative monitoring protein blood level rebound tenderness refractory disease repeat procedure Rhizopus microsporus sepsis septic shock surgical debridement surgical ward tachycardia wound complication |
| Journal or Publication Title: | Infectious Microbes and Diseases |
| Journal Index: | Scopus |
| Volume: | Publis |
| Identification Number: | https://doi.org/10.1097/IM9.0000000000000197 |
| ISSN: | 20967241 (ISSN) |
| Depositing User: | خانم ناهید ضیائی |
| URI: | http://eprints.mui.ac.ir/id/eprint/32580 |
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