Comparing three methods of dexamethasone, pethidine and hyoscine in prophylaxis of postoperative shivering after general anesthesia

Abstract

Background: Prevention and control of shivering after surgery is of significant importance and different methods are used for this purpose. In this study, three drugs of dexamethason, petidine and hyoscine were compared in the prevention of postoperative shivering. Methods: In a clinical trial study, 90 patients who were candidates for laparascopic cholesistectomia were selected and randomly divided in three equal groups. The first group received 0.5 mg/kg pethidine, the second group 0.1 mg/kg dexamethason and the third group 0.15 mg/kg hyoscine. The prevalence of postoperative shivering was compared between the three groups. The data was analyzed using SPSS software. Findings: In three groups of pethidine, hyoscine and dexamethason, 60, 43.3 and 54.4 had no postoperative shivering, respectively. In these groups, 20.0, 13.3 and 23.3 had mild shivering, 16.7, 33.3 and 6.7 had moderate shivering and 3.3., 10.0 and 10.0 had sever postoperative shivering, respectively, and no statistically difference were seen between the three groups (P = 0.16). Pain was lower in pethidine group than the other groups. In addition, dexamethasone and hyoscine had positive effects of postoperative nausea and methoclopramide consumption. Conclusion: Three drugs of pethidine, hyoscine and dexamethason have not different effects of prevention of postoperative shivering but the complications such were different. We recommend that in future studies, the combined effect of these drugs on postoperative complications in patients undergoing surgical procedures could be studied. © 2010, Isfahan University of Medical Sciences(IUMS). All rights reserved.