Estimating the activity of heart, liver and kidneys in myocardial perfusion scan with 99MTC-MIBI using conjugate view method

Abstract

Background: The estimation of patient absorbed dose is the first step of radiation protection that depends on quantification of organ activity in nuclear medicine. The aim of this study was estimating the organ activity for the purpose of calculating the dose and predicting radiation risks. Methods: The anterior and posterior images of volunteers were taken at 15, 60 and 120 minutes after the injection, either at rest or during exercise. Then, the organ activity was calculated using the conjugate view method, and also uptake of99mTC-MIBI was determined. Findings: The activity in the heart, liver and kidneys ranged 0.10-0.45, 0.26-4.19 and 0.68-2.03 mCi, respectively, in rest and 0.14-0.65, 0.47-2.70 and 0.46-2.63 mCi after the exercise. The uptake was 0.6-3.5, 1.4-23.1 and 2.6-14.1 percent of injected dose (ID) in heart, liver and kidney, respectively. Conclusion: The results of this study were in good agreement with similar studies. So, the conjugated view method with conventional method for background correction is an accurate approach for quantification of organ activity in myocardial perfusion scan. © 2015, Isfahan University of Medical Sciences(IUMS). All rights reserved.