Evaluation of the mean percentages of the peripheral blood gamma delta T lymphocytes in the healthy subjects and celiac patients in Isfahan

Abstract

Background: An elevation in the mean percentages of the gamma delta T lymphocytes per total T cells in the epithelium of the small intestine has a diagnostic value for celiac disease. This study aimed to measure the percentages of the peripheral blood gamma delta T lymphocytes in the adults' celiac disease and healthy controls. Materials and Methods: In this case-control study the absolute numbers of the peripheral blood lymphocytes obtained from the controls (n = 21) and celiac patients (n=15) were studied, Using a cell counter. The proportions of the gamma-delta T lymphocytes were evaluated by the flow cytometer method. Results: The results showed that there was not significant I difference in the percentages of the gamma-delta T lymphocytes between celiac patients and healthy individuals. (p value= 0.84) Conclusion: Collectively, the data show that the percentages of the peripheral blood gamma delta T lymphocytes could not be helpful for celiac disease diagnosis.