Features and roles of T helper 9 cells and interleukin 9 in immunological diseases

(2019) Features and roles of T helper 9 cells and interleukin 9 in immunological diseases. ALLERGOLOGIA ET IMMUNOPATHOLOGIA. ISSN 1578-1267 (Electronic) 0301-0546 (Linking)

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Abstract

T helper 9 (TH9) cells are considered as newly classified helper T cells that have an important role in the regulation of immune responses. Since these cells preferentially produce IL-9, these cells are termed TH9 cells. Recently, the role of TH9 and its signature cytokine (IL-9) has been investigated in a wide range of diseases, including autoimmunity, allergy, infections, cancer and immunodeficiency. Herein, we review the most recent data concerning TH9 cells and IL-9 as well as their roles in disease. These insights suggest that TH9 cells are a future target for therapeutic intervention.

Item Type: Article
Keywords: Allergic Autoimmunity Cancer Il-9 Immunodeficiency Infections T(H)9 cells
Subjects: QW Microbiology and Immunology > QW 501-949 Immunology
Divisions: Faculty of Medicine > Department of Basic Science > Immunology Department
Journal or Publication Title: ALLERGOLOGIA ET IMMUNOPATHOLOGIA
Journal Index: ISI
Identification Number: https://doi.org/10.1016/j.aller.2018.02.003
ISSN: 1578-1267 (Electronic) 0301-0546 (Linking)
Depositing User: Zahra Otroj
URI: http://eprints.mui.ac.ir/id/eprint/8061

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