Plant-Derived Edible Nanoparticles and miRNAs: Emerging Frontier for Therapeutics and Targeted Drug-Delivery

(2019) Plant-Derived Edible Nanoparticles and miRNAs: Emerging Frontier for Therapeutics and Targeted Drug-Delivery. Acs Sustainable Chemistry & Engineering. pp. 8055-8069. ISSN 2168-0485

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Abstract

Rigorous and timely studies have been conducted to develop natural and green nanomedicines wherein plant-derived edible nanoparticles (PDENs) have a great potential to be applied for targeted therapeutic delivery systems, because of their exclusive characteristics, namely desirable nanoparticle morphologies, environmentally safe and nonhazardous nature, appropriate tissue-specific targeting, and eminent potential for industrial pharmaceutical production. These nanoparticles can be exploited for drug transportation with distinctive benefits for treatment of diseases like cancers. In this Perspective, the properties and applications of PDENs are discussed with latest developments including the recent trends in plant-derived edible exosome-like nanoparticles and miRNAs.

Item Type: Article
Keywords: plant-derived nanoparticles mirnas edible nanoparticles therapeutic delivery colon cancer drug delivery systems tumor cells inflammatory-bowel-disease green synthesis micrornas exosomes nanovesicles cells sirna colitis rna nanotechnology
Subjects: QV Pharmacology
Divisions: Faculty of Pharmacy and Pharmaceutical Sciences
Page Range: pp. 8055-8069
Journal or Publication Title: Acs Sustainable Chemistry & Engineering
Journal Index: ISI
Volume: 7
Number: 9
Identification Number: https://doi.org/10.1021/acssuschemeng.9b00954
ISSN: 2168-0485
Depositing User: Zahra Otroj
URI: http://eprints.mui.ac.ir/id/eprint/9994

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